兔多克隆抗体to Profilin 2
Recombinant protein fragment corresponding to a region within amino acids 1 and 120 of Human Profilin 2 (NP_002619).
293T, A431, H1299, HeLaS3, HepG2, MOLT4 and Raji cell lysates
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 15 kDa.
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Belongs to the profilin family.
Cytoplasm > cytoskeleton.
Information by UniProt
PFN 2 antibody
Anti-Profilin 2 antibody 图像
Anti-Profilin 2 antibody (ab96676)参考文献
has not yet been referenced specifically in any publications.
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