The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
功能Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
组织特异性Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Predicted band size : 15 kDa Profilin 2 antibody (ab55611) at 1ug/lane + HeLa cell lysate at 25ug/lane.
Anti-Profilin 2 antibody (ab55611)参考文献
This product has been referenced in:
Liu HP et al. Proteome-wide Dysregulation by PRA1 Depletion Delineates a Role of PRA1 in Lipid Transport and Cell Migration. Mol Cell Proteomics10:M900641MCP200 (2011).
Read more (PubMed: 20592422) »