概述

  • 产品名称Anti-Profilin 2抗体
    参阅全部 Profilin 2 一抗
  • 描述
    小鼠单克隆抗体to Profilin 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: QSITPIEIDM IVGKDREGFF TNGLTLGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRAL VIVMGKEGVH GGTLNKKAYE LALYLRRSDV , corresponding to amino acids 41-141 of Human Profilin 2

性能

应用

Our Abpromise guarantee covers the use of ab55611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
    • 组织特异性Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
    • 序列相似性Belongs to the profilin family.
    • 细胞定位Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 数据库链接
    • 别名
      • D3S1319E antibody
      • PFL antibody
      • PFN 2 antibody
      • Pfn2 antibody
      • PROF2_HUMAN antibody
      • Profilin II antibody
      • Profilin-2 antibody
      • Profilin2 antibody
      • ProfilinII antibody
      see all

    Anti-Profilin 2 antibody 图像



    • Predicted band size : 15 kDa
      Profilin 2 antibody (ab55611) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-Profilin 2 antibody (ab55611)参考文献

    This product has been referenced in:
    • Liu HP  et al. Proteome-wide Dysregulation by PRA1 Depletion Delineates a Role of PRA1 in Lipid Transport and Cell Migration. Mol Cell Proteomics 10:M900641MCP200 (2011). WB ; Human . Read more (PubMed: 20592422) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"