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Hedgehog signaling
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Cancer

Hedgehog signaling pathway: an overview

Read our overview of the hedgehog signaling pathway. Includes Hh signaling cascade in Drosophila and Hh signaling orthologues in vertebrates.

Product image

GANT 61 (ab120904)

Description:
Selective GLI1 and 2 inhibitor
Purity:
> 98%

Cyclopamine (ab120392)

Description:
Hh signaling inhibitor
Purity:
> 98%
Product image

Jervine (ab120815)

Description:
Smoothened inhibitor
Purity:
> 98%

QVD-OPh (ab141421)

Description:
Potent, cell-permeable, irreversible broad-spectrum caspase inhibitor
Purity:
> 95%
Product image

Z-IETD-FMK (ab141382)

Description:
Caspase-8 inhibitor
Purity:
> 99%

GANT58 (ab120665)

Description:
Downstream Hh signaling inhibitor
Purity:
> 99%

MRT-10 (ab141191)

Description:
Novel, high affinity smoothened (Smo) antagonist
Purity:
> 99%

Purmorphamine (ab120933)

Description:
Smoothened receptor agonist
Purity:
> 98%

SANT-1 (ab141483)

Description:
Potent smoothened and hedgehog signaling antagonist
Purity:
> 98%

SANT-2 (ab141481)

Description:
Potent smoothened receptor antagonist
Purity:
> 95%
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