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Cancer
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Cancer

Structure and dynamics of microtubules

Microtubules are composed of alpha- and beta-tubulins and function as one of the most important cytoskeleton elements. Read this article to find out more about their structure and dynamics, as well as about the effect that different microtubule targeting agents have.

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(±)-Blebbistatin (ab120425)

Description:
Potent, selective, inhibitor of myosin II
Purity:
> 99%
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Forskolin (ab120058)

Description:
Adenylyl cyclase activator
Purity:
> 98%
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Y-27632 dihydrochloride (ab120129)

Description:
Selective Rho kinase inhibitor
Purity:
> 99%
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Thapsigargin (ab120286)

Description:
Ca2+-ATPase inhibitor
Purity:
> 98%
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Ionomycin Ca2+ Salt (ab120116)

Description:
Ca2+ ionophore
Purity:
> 99%
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LY 294002 (ab120243)

Description:
PI3-kinase inhibitor
Purity:
> 99%
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U0126 (ab120241)

Description:
Selective MKK inhibitor
Purity:
> 98%

Z-VAD(OH)-FMK (ab120382)

Description:
Irreversible general caspase inhibitor
Purity:
> 97%
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BAPTA-AM (ab120503)

Description:
Selective Ca2+ chelator. Analog of BAPTA.
Purity:
> 97%
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Ryanodine (ab120083)

Description:
Ca2+ release modulator
Purity:
> 98%
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