Anti-Procathepsin K抗体[4b9] (ab39246)

概述

  • 产品名称Anti-Procathepsin K抗体[4b9]
  • 描述
    小鼠单克隆抗体[4b9] to Procathepsin K
  • 特异性This antibody is specific for Procathepsin K.
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    N terminal His-tagged recombinant fusion protein (Human), produced in E. coli (36.7 kDa). It comprised 314 amino acid residues of the Human Procathepsin K and 12 additional amino acid residues (MRGSHHHHHHGS) - His Tag.

性能

应用

Our Abpromise guarantee covers the use of ab39246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 27 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
  • 组织特异性Predominantly expressed in osteclasts (bones).
  • 疾病相关Defects in CTSK are the cause of pycnodysostosis (PKND) [MIM:265800]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.
  • 序列相似性Belongs to the peptidase C1 family.
  • 细胞定位Lysosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cathepsin K antibody
    • Cathepsin O antibody
    • Cathepsin O1 antibody
    • Cathepsin O2 antibody
    • Cathepsin X antibody
    • CATK_HUMAN antibody
    • Ctsk antibody
    • CTSO antibody
    • CTSO2 antibody
    • PKND antibody
    • PYCD antibody
    see all

Anti-Procathepsin K antibody [4b9] (ab39246)参考文献

ab39246 has not yet been referenced specifically in any publications.

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