Anti-Procalcitonin抗体[42] (HRP) (ab24454)

概述

  • 产品名称Anti-Procalcitonin抗体[42] (HRP)
    参阅全部 Procalcitonin 一抗
  • 描述
    小鼠单克隆抗体[42] to Procalcitonin (HRP)
  • 偶联物HRP
  • 特异性Specific for N-terminal fragment.
  • 经测试应用适用于: Sandwich ELISA, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment (Human)

  • 表位aa 21-40

性能

应用

Our Abpromise guarantee covers the use of ab24454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [16B5] to Calcitonin (ab11493). Can be used as Detection antibody.
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [16B5] to Calcitonin (ab11493).
WB Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.

靶标

  • 相关性Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • CALC1 antibody
    • CALCA antibody
    • calcitonin related polypeptide alpha antibody
    • CGRP antibody
    • CGRP1 antibody
    • CT antibody
    • katacalcin antibody
    • KC antibody
    see all

Anti-Procalcitonin antibody [42] (HRP) (ab24454)参考文献

ab24454 has not yet been referenced specifically in any publications.

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The procalcitonin antibody ab24454 has not been tested for reactivity with canine procalcitonin but an alignment of the immunogen sequence with the canine protein's amino acid sequence shows 71% identity. The for...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"