Anti-Procalcitonin抗体[13F2] (ab90489)

概述

  • 产品名称Anti-Procalcitonin抗体[13F2]
    参阅全部 Procalcitonin 一抗
  • 描述
    小鼠单克隆抗体[13F2] to Procalcitonin
  • 特异性It recognises calcitonin and procalcitonin
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human Calcitonin conjugated with carrier protein

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明ab90489 was purified by Protein A chromatography from ascites and is >90% pure as assessed by SDS-PAGE
  • 克隆单克隆
  • 克隆编号13F2
  • 骨髓瘤Sp2/0
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab90489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 13 kDa.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution.

靶标

  • 相关性Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • CALC1 antibody
    • CALCA antibody
    • calcitonin related polypeptide alpha antibody
    • CGRP antibody
    • CGRP1 antibody
    • CT antibody
    • katacalcin antibody
    • KC antibody
    see all

Anti-Procalcitonin antibody [13F2] 图像

  • Anti-Procalcitonin antibody [13F2] (ab90489) at 1 µg/ml + Recombinant human Procalcitonin protein (ab92843) at 0.1 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 3 minutes

Anti-Procalcitonin antibody [13F2] (ab90489)参考文献

ab90489 has not yet been referenced specifically in any publications.

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