概述

  • 产品名称
  • 描述
    山羊多克隆抗体to proBNP
  • 特异性
    Synthetic human proBNP (aa 32-57). There were no cross reactivities obtained with human proBNP (aa 8-29).
  • 经测试应用
    适用于: Sandwich ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    QVEQTSLEPLQESPRPTGVWKSREVA

    , corresponding to amino acids 32-57 of Human proBNP.

性能

应用

Our Abpromise guarantee covers the use of ab14352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA 1/5000.

Suitable for use as capture antibody in sandwich ELISA.

IHC-P 1/100.

靶标

  • 功能
    Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 组织特异性
    Brain and also in atria, but at much lower levels than ANP.
  • 序列相似性
    Belongs to the natriuretic peptide family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANFB_HUMAN antibody
    • BNP antibody
    • BNP(1-32) antibody
    • BNP(5-29) antibody
    • BNP-32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Gamma-brain natriuretic peptide antibody
    • Natriuretic peptide precursor B antibody
    • nppb antibody
    • NT proBNP antibody
    see all

文献

ab14352 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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