Anti-NT-proBNP抗体[15F11] (ab13115)
Key features and details
- Mouse monoclonal [15F11] to NT-proBNP
- Suitable for: ELISA, WB
- Reacts with: Recombinant fragment
- Isotype: IgG2b
概述
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产品名称
Anti-NT-proBNP抗体[15F11]
参阅全部 NT-proBNP 一抗 -
描述
小鼠单克隆抗体[15F11] to NT-proBNP -
宿主
Mouse -
经测试应用
适用于: ELISA, WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Synthetic peptide corresponding to Human NT-proBNP aa 1-100.
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常规说明
Immunoglobulin concentrations vary from batch to batch. Please contact technical services for the latest information.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.09% Sodium azide -
Concentration information loading...
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纯度
Protein A purified -
纯化说明
Chromatography on protein A Sepharose -
克隆
单克隆 -
克隆编号
15F11 -
同种型
IgG2b -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab13115于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Detects a band of approximately 13 kDa.
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说明 |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Detects a band of approximately 13 kDa. |
靶标
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功能
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. -
组织特异性
Brain and also in atria, but at much lower levels than ANP. -
序列相似性
Belongs to the natriuretic peptide family. -
细胞定位
Secreted. - Information by UniProt
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别名
- ANFB_HUMAN antibody
- BNP(1-32) antibody
- BNP(5-29) antibody
see all
图片
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WB detecting proBNP showing comparable detection from a range of antibodies available. Lane 1 - ab13111 [5B6], lane 2 - ab13115 [15F11], lane 3 - ab13059 [11D1], lane 4 - ab13124 [15D7], lane 5 - ab13122 [13C1], lane 6 ab13123 [24E11]. WB detecting proBNP showing comparable detection from a range of antibodies available. Lane 1 - ab13111 [5B6], lane 2 - ab13115 [15F11], lane 3 - ab13059 [11D1], lane 4 - ab13124 [15D7], lane 5 - ab13122 [13C1], lane 6 ab13123 [24E11].
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab13115 被引用在 6 文献中.
- Knight WE et al. A simple protocol to produce mature human-induced pluripotent stem cell-derived cardiomyocytes. STAR Protoc 2:100912 (2021). PubMed: 34755117
- Karhu ST et al. GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytes. Arch Toxicol 94:2113-2130 (2020). PubMed: 32185414
- Pohjolainen L et al. Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Front Pharmacol 11:553852 (2020). PubMed: 33584253
- Mosqueira D et al. High-Throughput Phenotyping Toolkit for Characterizing Cellular Models of Hypertrophic Cardiomyopathy In Vitro. Methods Protoc 2:N/A (2019). PubMed: 31717790
- Nagai H et al. Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia. EBioMedicine 24:147-158 (2017). PubMed: 28942281
- Tonne JM et al. Secretion of glycosylated pro-B-type natriuretic peptide from normal cardiomyocytes. Clin Chem 57:864-73 (2011). IP ; Human . PubMed: 21482747