概述

  • 产品名称
  • 描述
    羊多克隆抗体to proANP
  • 特异性
    Synthetic human proANP (aa 31-67). There were no cross reactivities obtained with human proANP (aa 67-98) and human proANP (aa 1-30).
  • 经测试应用
    适用于: ELISA, RIAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit, Cat, Dog, Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide:

    EVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQR

    , corresponding to amino acids 31-67 of Human proANP.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab14349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
RIA 1/2000.

靶标

  • 功能
    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 疾病相关
    Atrial standstill 2
    Atrial fibrillation, familial, 6
  • 序列相似性
    Belongs to the natriuretic peptide family.
  • 翻译后修饰
    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANF antibody
    • ANF_HUMAN antibody
    • ANP antibody
    • ATFB6 antibody
    • Atrial natriuretic factor antibody
    • Atrial natriuretic peptide antibody
    • Atriopeptin antibody
    • ATRST2 antibody
    • Cardiodilatin antibody
    • Cardiodilatin-related peptide antibody
    • Cardionatrin antibody
    • CDD ANF antibody
    • CDD antibody
    • CDD-ANF antibody
    • CDP antibody
    • Natriuretic peptide A antibody
    • Natriuretic peptide precursor A antibody
    • Natriuretic peptides A antibody
    • NPPA antibody
    • PND antibody
    • Prepronatriodilatin antibody
    • Pronatriodilatin antibody
    see all

Anti-proANP antibody (ab14349)参考文献

ab14349 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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