概述

  • 产品名称Anti-PRKX抗体[EPR4840]
    参阅全部 PRKX 一抗
  • 描述
    兔单克隆抗体[EPR4840] to PRKX
  • 经测试应用适用于: WB, ICC, Flow Cytmore details
    不适用于: IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    synthetic peptide corresponding to residues in human PRKX

  • 阳性对照
    • FC: permeabilized A549 cells; WB: A549, Jurkat, 293T, fetal kidney and fetal brain lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab109389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
ICC 1/100 - 1/250.
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for IHC-P or IP.
  • 靶标

    • 组织特异性High levels in adult and fetal brain, kidney and lung; low levels in adult placenta, heart, liver, skeletal muscle, pancreas and fetal liver.
    • 疾病相关Note=A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.
    • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • PKX1 antibody
      • PRKX antibody
      • PRKX_HUMAN antibody
      • Protein kinase PKX1 antibody
      • Serine/threonine-protein kinase PRKX antibody
      see all

    Anti-PRKX antibody [EPR4840] 图像

    • All lanes : Anti-PRKX antibody [EPR4840] (ab109389) at 1/1000 dilution

      Lane 1 : A549 cell lysates
      Lane 2 : Jurkat cell lysates
      Lane 3 : 293T cell lysates
      Lane 4 : Human fetal kidney lysates
      Lane 5 : Human fetal brain lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 41 kDa

    Anti-PRKX antibody [EPR4840] (ab109389)参考文献

    This product has been referenced in:
    • Ouyang C  et al. Transforming Growth Factor (TGF)-ß-activated Kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit a (PKACa) and X-linked Protein Kinase (PRKX). J Biol Chem 289:24226-37 (2014). WB . Read more (PubMed: 25028512) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"