Anti-Prickle抗体(ab15577)
Key features and details
- Rabbit polyclonal to Prickle
- Suitable for: ELISA
- Isotype: IgG
概述
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产品名称
Anti-Prickle抗体 -
描述
兔多克隆抗体to Prickle该产品是 快线抗体,通过亲和纯化得到。对抗原肽有高灵敏度及特异性(ELISA测试)。 Read the terms of use »
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宿主
Rabbit -
特异性
Immunogen sequence most homologous with Prickle 1, but is ~65% identical with Prickle 2 sequences, thus some reaction with Prickle 2 may be seen as well as with Prickle 1. -
种属反应性
预测可用于: Mouse, Rat, Human, Xenopus laevis, Zebrafish -
免疫原
Synthetic peptide corresponding to Xenopus laevis Prickle aa 300-400 (internal sequence) conjugated to keyhole limpet haemocyanin.
(Peptide available asab15578) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab15578).
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说明 |
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ELISA
Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab15578). |
靶标
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相关性
Prickle is a LIM domain protein that appears to serve as a nuclear receptor for REST/NRSF, REST4, and possibly other transcription factors. The human protein is a 831 amino acid protein containing 3 N-terminal LIM domains and 3 C-terminal nuclear localization signals. It also contains 4 N-glycosylation sites, 2 PKA phosphorylation sites, and a C-terminal CIIS prenylation motif. -
细胞定位
Nuclear Membrane -
数据库链接
- Entrez Gene: 144165 Human
- Entrez Gene: 106042 Mouse
- Entrez Gene: 315259 Rat
- Entrez Gene: 368249 Zebrafish
- Omim: 608500 Human
- SwissProt: Q14C83 Human
- SwissProt: Q96MT3 Human
- SwissProt: Q3U5C7 Mouse
see all -
别名
- FLJ31627 antibody
- FLJ31937 antibody
- MGC138902 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab15577 被引用在 4 文献中.
- Kotrbová A et al. WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer. Theranostics 10:537-552 (2020). PubMed: 31903136
- Gignac SJ et al. Robinow syndrome skeletal phenotypes caused by the WNT5AC83S variant are due to dominant interference with chondrogenesis. Hum Mol Genet 28:2395-2414 (2019). PubMed: 31032853
- Wan Y et al. Prickle1 regulates differentiation of frontal bone osteoblasts. Sci Rep 8:18021 (2018). PubMed: 30575813
- Song H et al. Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/ß-catenin signaling. EBioMedicine 35:155-166 (2018). PubMed: 30150059