概述

  • 产品名称Anti-PREX1抗体
    参阅全部 PREX1 一抗
  • 描述
    山羊多克隆抗体to PREX1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    C-ERSNLPTDASTTA

    , corresponding to internal sequence amino acids 1514-1526 of Human PREX1 (NP_065871.2).

  • 阳性对照
    • Human temporal cortex lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab99425 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab99425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 186 kDa.

靶标

  • 功能Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol-3,4,5-triphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
  • 组织特异性Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
  • 序列相似性Contains 1 DEP domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PDZ (DHR) domain.
    Contains 2 PH domains.
  • 细胞定位Cytoplasm > cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4 antibody
    • 5)-dependent Rac exchanger 1 antibody
    • KIAA1415 antibody
    • OTTHUMP00000031228 antibody
    • P REX1 antibody
    • P Rex1 protein like antibody
    • P-Rex1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein antibody
    • Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody
    • Prex1 antibody
    • PREX1_HUMAN antibody
    • PtdIns(3 antibody
    • PtdIns(3,4,5) dependent Rac exchanger 1 antibody
    • SET domain containing 6 antibody
    • Setd6 antibody
    see all

Anti-PREX1 antibody 图像

  • Anti-PREX1 antibody (ab99425) at 1 µg/ml + Human temporal cortex lysate at 35 µg

    Predicted band size : 186 kDa

Anti-PREX1 antibody (ab99425)参考文献

ab99425 has not yet been referenced specifically in any publications.

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