概述

  • 产品名称Anti-PREX1抗体
    参阅全部 PREX1 一抗
  • 描述
    兔多克隆抗体to PREX1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 1133-1163 of Human PREX1 (NP_065871.2).

  • 阳性对照
    • NCI-H460 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab112950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 186 kDa.

靶标

  • 功能Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol-3,4,5-triphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
  • 组织特异性Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
  • 序列相似性Contains 1 DEP domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PDZ (DHR) domain.
    Contains 2 PH domains.
  • 细胞定位Cytoplasm > cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4 antibody
    • 5)-dependent Rac exchanger 1 antibody
    • KIAA1415 antibody
    • OTTHUMP00000031228 antibody
    • P REX1 antibody
    • P Rex1 protein like antibody
    • P-Rex1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 antibody
    • Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein antibody
    • Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody
    • Prex1 antibody
    • PREX1_HUMAN antibody
    • PtdIns(3 antibody
    • PtdIns(3,4,5) dependent Rac exchanger 1 antibody
    • SET domain containing 6 antibody
    • Setd6 antibody
    see all

Anti-PREX1 antibody 图像

  • Anti-PREX1 antibody (ab112950) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

    Predicted band size : 186 kDa

Anti-PREX1 antibody (ab112950)参考文献

ab112950 has not yet been referenced specifically in any publications.

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