Anti-Prepronociceptin抗体(ab98152)

概述

  • 产品名称Anti-Prepronociceptin抗体
    参阅全部 Prepronociceptin 一抗
  • 描述
    兔多克隆抗体to Prepronociceptin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish, Spider Monkey
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 107-156 (EQEEPEPGME EAGEMEQKQL QKRFGGFTGA RKSARKLANQ KRFSEFMRQY) of Human Prepronociceptin (NP_006219).

  • 阳性对照
    • HepG2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab98152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
  • 组织特异性Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation.
  • 序列相似性Belongs to the opioid neuropeptide precursor family.
  • 翻译后修饰Specific enzymatic cleavages at paired basic residues probably yield other active peptides besides nociceptin.
    The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Neuropeptide 2 antibody
    • OFQ antibody
    • Orphanin FQ antibody
    • Pnoc antibody
    • PNOC_HUMAN antibody
    • PPNOC antibody
    see all

Anti-Prepronociceptin antibody 图像

  • Anti-Prepronociceptin antibody (ab98152) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 20 kDa

Anti-Prepronociceptin antibody (ab98152)参考文献

ab98152 has not yet been referenced specifically in any publications.

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