Anti-PRDM3抗体[47AT612.84.88] (ab3792)

概述

  • 产品名称
    Anti-PRDM3抗体[47AT612.84.88]
  • 描述
    小鼠单克隆抗体[47AT612.84.88] to PRDM3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Fusion protein (GST-tag) corresponding to Human PRDM3 aa 43-208 (N terminal).

  • 阳性对照
    • WB: 293 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab3792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 130 kDa.

靶标

  • 相关性
    PRDM3 can be produced either as a separate transcript and as a fusion transcript with EVI1. A chromosomal aberration involving PRDM3 is found in a form of acute myeloid leukemia. The myelodysplastic syndromes (MDS, formerly known as "preleukemia") are a diverse collection of hematological conditions united by ineffective production of blood cells and varying risks of transformation to acute myelogenous leukemia.
  • 数据库链接
  • 别名
    • MDS1 antibody
    • MDS1 EVI1 antibody
    • MDS1EVI1 antibody
    • Myelodysplasia syndrome 1 antibody
    • Myelodysplasia syndrome associated protein 1 antibody
    • PRDM 3 antibody
    • PRDM3 antibody
    see all

实验方案

文献

This product has been referenced in:
  • Sgourdou P  et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep 7:43708 (2017). Read more (PubMed: 28272472) »
  • Jablonski AM  et al. Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. J Neurosci 35:14286-306 (2015). Read more (PubMed: 26490867) »

See all 3 Publications for this product

客户评价及客户问答

Thank you for your enquiry. This antibody was raised using purified recombinant GST fusion protein encoding the 43-208 aa of human PRDM3. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

It was made against recombinant protein corresponding to the N-term (1-300aa) of human MDS-1 (NM_004991). it should not react with EVI1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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