Anti-PRDM1/Blimp1抗体[3H2-E8] (Biotin) (ab81961)


  • 产品名称Anti-PRDM1/Blimp1抗体[3H2-E8] (Biotin)
    参阅全部 PRDM1/Blimp1 一抗
  • 描述
    小鼠单克隆抗体[3H2-E8] to PRDM1/Blimp1 (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: WB, ICC, ICC/IF, IHC-Pmore details
    不适用于: IP
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Protein fragment, corresponding to amino acids 199-409 of Mouse PRDM1/Blimp1

  • 阳性对照
    • P3X (murine plasmocytoma) cell lysates.



Our Abpromise guarantee covers the use of ab81961 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 95 kDa.
ICC 1/50 - 1/100.
ICC/IF 1/200.
IHC-P Use at an assay dependent dilution.
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
    • 序列相似性Belongs to the class V-like SAM-binding methyltransferase superfamily.
      Contains 4 C2H2-type zinc fingers.
      Contains 1 SET domain.
    • 翻译后修饰Sumoylation at Lys-816 by PIAS1 augments transcriptional repressor activity, and is critical for plasma cell differentiation.
      Ubiquitinated by the SCF(FBXO11) complex, leading to its degradation by the proteasome.
    • 细胞定位Nucleus. Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B Lymphocyte Induced Maturation Protein 1 antibody
      • Beta interferon gene positive regulatory domain I binding factor antibody
      • Beta-interferon gene positive regulatory domain I-binding factor antibody
      • BLIMP-1 antibody
      • BLIMP1 antibody
      • Positive Regulatory Domain I Binding Factor 1 antibody
      • Positive regulatory domain I-binding factor 1 antibody
      • PR Domain Containing 1 antibody
      • PR domain containing 1 with ZNF domain antibody
      • PR domain containing 1 with ZNF domain isoform 2 antibody
      • PR domain containing protein 1 antibody
      • PR domain zinc finger protein 1 antibody
      • PR domain-containing protein 1 antibody
      • PRDI BF1 antibody
      • PRDI binding factor 1 antibody
      • PRDI-BF1 antibody
      • PRDI-binding factor 1 antibody
      • PRDM 1 antibody
      • Prdm1 antibody
      • PRDM1_HUMAN antibody
      see all

    Anti-PRDM1/Blimp1 antibody [3H2-E8] (Biotin) (ab81961)参考文献

    ab81961 has not yet been referenced specifically in any publications.

    Product Wall

    Application Flow Cytometry
    Fixation Formaldehyde
    Permeabilization Yes - Triton X100
    Sample Mouse Cell (spleen cells)
    Specification spleen cells
    Gating Strategy CD8 T cells
    Preparation Cell harvesting/tissue preparation method: single cell suspension
    Sample buffer: PBS / FCS

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    提交于 Jun 19 2013

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