Anti-PRAX-1抗体(ab121856)
Key features and details
- Rabbit polyclonal to PRAX-1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-PRAX-1抗体 -
描述
兔多克隆抗体to PRAX-1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence: RTASTSTLGE KDPGPAAPSL AKQEAEWTAG EACPASSSTQ GARAQQAPNT EMCQGGDPGS GLRPRAEKED TAELGVHLVN SLVDHGRNSD LSD, corresponding to internal sequence amino acids 1167-1259 of Human PRAX-1.
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阳性对照
- Human esophagus tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121856于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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组织特异性
Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus. -
序列相似性
Belongs to the RIMBP family.
Contains 3 fibronectin type-III domains.
Contains 3 SH3 domains. -
结构域
The SH3 and proline-rich domain is required for the interaction with BZRP and the second SH3 domain mediates binding to a proline-rich motif in RIMS1 and RIMS2. -
细胞定位
Cytoplasm. Mitochondrion. Preferentially expressed in the mitochondria in the presence of BZRP. - Information by UniProt
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数据库链接
- Entrez Gene: 9256 Human
- Omim: 610764 Human
- SwissProt: O95153 Human
- Unigene: 112499 Human
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别名
- Bzrap1 antibody
- D230016K05 antibody
- mKIAA0612 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab121856 被引用在 1 文献中.
- Liu D et al. microRNA-155 Modulates Hepatic Stellate Cell Proliferation, Apoptosis, and Cell Cycle Progression in Rats With Alcoholic Hepatitis via the MAPK Signaling Pathway Through Targeting SOCS1. Front Pharmacol 11:270 (2020). PubMed: 32317960