概述

  • 产品名称
    Anti-PRAME抗体
    参阅全部 PRAME 一抗
  • 描述
    兔多克隆抗体to PRAME
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide from within residues: MVQAWPFTCL PLGVLMKGQH LHLETFKAVL DGLDVLLAQE VRPRRWKLQV , corresponding to N terminal amino acids 72-121 of Human PRAME (NP_006106)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • 阳性对照
    • HepG2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab90053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
  • 组织特异性
    Expressed in testis. Detected in samples of kidney, brain and skin.
  • 序列相似性
    Belongs to the PRAME family.
    Contains 4 LRR (leucine-rich) repeats.
  • 细胞定位
    Nucleus. Cell membrane.
  • Information by UniProt
  • 数据库链接
    • 别名
      • 4930534P07Rik antibody
      • Cancer/testis antigen 130 antibody
      • CT130 antibody
      • MAPE antibody
      • Melanoma antigen preferentially expressed in tumors antibody
      • OIP 4 antibody
      • OIP-4 antibody
      • OIP4 antibody
      • OPA interacting protein 4 antibody
      • Opa interacting protein OIP4 antibody
      • OPA-interacting protein 4 antibody
      • PRAME antibody
      • PRAME_HUMAN antibody
      • Preferentially expressed antigen in melanoma antibody
      • Preferentially expressed antigen of melanoma antibody
      • RP23-250F8.3 antibody
      see all

    图片

    • Western blot - Anti-PRAME antibody (ab90053)
      Western blot - Anti-PRAME antibody (ab90053)
      Anti-PRAME antibody (ab90053) at 1 µg/ml + HepG2 cell lysate at 10 µg

      Secondary
      HRP conjugated anti-Rabbit IgG at 1/50000 dilution

      Predicted band size: 58 kDa

    实验方案

    文献

    ab90053 has not yet been referenced specifically in any publications.

    发表研究结果有使用 ab90053？请让我们知道，以便我们可以引用本数据表中的参考文章。

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