Anti-PRAME抗体(ab90053)

概述

• 产品名称
  Anti-PRAME抗体
  参阅全部 PRAME 一抗
• 描述
  兔多克隆抗体to PRAME
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat, Cow
• 免疫原

  Synthetic peptide from within residues: MVQAWPFTCL PLGVLMKGQH LHLETFKAVL DGLDVLLAQE VRPRRWKLQV , corresponding to N terminal amino acids 72-121 of Human PRAME (NP_006106)

  Run BLAST with Run BLAST with
• 阳性对照
  • HepG2 cell lysate

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• 存储溶液
  Preservative: None
  Constituents: 2% Sucrose, PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Tags & Cell Markers
  • Cell Type Markers
  • Tumor Associated

  • Epigenetics and Nuclear Signaling
  • Nuclear Signaling Pathways
  • Nuclear Receptors
  • Co-activators/co-repressors

  • Cancer
  • Tumor biomarkers
  • Tumor antigens

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • HepG2 nuclear extract lysate (ab14660)

应用

靶标

• 功能
  Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
• 组织特异性
  Expressed in testis. Detected in samples of kidney, brain and skin.
• 序列相似性
  Belongs to the PRAME family.
  Contains 4 LRR (leucine-rich) repeats.
• 细胞定位
  Nucleus. Cell membrane.

• Target information above from: UniProt accession P78395 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 23532 Human
  • Entrez Gene: 75829 Mouse
  • Entrez Gene: 680000 Rat
  • Omim: 606021 Human
  • SwissProt: P78395 Human
  • Unigene: 30743 Human
• 别名
  • 4930534P07Rik antibody
  • Cancer/testis antigen 130 antibody
  • CT130 antibody

  • MAPE antibody
  • Melanoma antigen preferentially expressed in tumors antibody
  • OIP 4 antibody
  • OIP-4 antibody
  • OIP4 antibody
  • OPA interacting protein 4 antibody
  • Opa interacting protein OIP4 antibody
  • OPA-interacting protein 4 antibody
  • PRAME antibody
  • PRAME_HUMAN antibody
  • Preferentially expressed antigen in melanoma antibody
  • Preferentially expressed antigen of melanoma antibody
  • RP23-250F8.3 antibody

  see all

实验方案

• Western blot protocols