概述

  • 产品名称Anti-PPP2R5A抗体
    参阅全部 PPP2R5A 一抗
  • 描述
    兔多克隆抗体to PPP2R5A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 108-157 (VSTNRGVIVE SAYSDIVKMI SANIFRTLPP SDNPDFDPEE DEPTLEASWP) of human PPP2R5A (NP_006234).

  • 阳性对照
    • Transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab86551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 组织特异性Widely expressed with the highest expression in heart and skeletal muscle.
  • 序列相似性Belongs to the phosphatase 2A regulatory subunit B56 family.
  • 翻译后修饰Phosphorylated on serine residues.
  • 细胞定位Cytoplasm. Nucleus. Chromosome > centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2A5A_HUMAN antibody
    • B56A antibody
    • MGC131915 antibody
    • PP2A B subunit B' alpha isoform antibody
    • PP2A B subunit B56 alpha isoform antibody
    • PP2A B subunit isoform B''-alpha antibody
    • PP2A B subunit isoform B56-alpha antibody
    • PP2A B subunit isoform PR61-alpha antibody
    • PP2A B subunit isoform R5-alpha antibody
    • PP2A B subunit PR61 alpha isoform antibody
    • PP2A B subunit R5 alpha isoform antibody
    • PPP2R5A antibody
    • PR61A antibody
    • PR61alpha antibody
    • Protein phosphatase 2 regulatory subunit B (B56) alpha isoform antibody
    • Protein phosphatase 2 regulatory subunit B' alpha antibody
    • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform antibody
    see all

Anti-PPP2R5A antibody 图像

  • Anti-PPP2R5A antibody (ab86551) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

Anti-PPP2R5A antibody (ab86551)参考文献

ab86551 has not yet been referenced specifically in any publications.

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