Synthetic peptide: AYNMHSILSNTSAE, corresponding to C terminal amino acids 473-486 of Human PPP2R5A.
- Human Heart and Muscle lysate.
GenBank Accession Number – NP_006234.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).Can be blocked with Human PPP2R5A peptide (ab22797).
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Widely expressed with the highest expression in heart and skeletal muscle.
Belongs to the phosphatase 2A regulatory subunit B56 family.
Phosphorylated on serine residues.
Cytoplasm. Nucleus. Chromosome > centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase.
Information by UniProt
- 2A5A_HUMAN antibody
- B56A antibody
- MGC131915 antibody
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