存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: 0.08% Sodium Azide
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纯度 Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 56 kDa.
1/500 - 1/1000.
Use at an assay dependent concentration. PubMed: 23887057
功能 The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
组织特异性 Expressed in all tissues examined.
序列相似性 Belongs to the phosphatase 2A regulatory subunit B family. Contains 7 WD repeats.
Information by UniProt
Alpha isoform of regulatory subunit B55 protein phosphatase 2 antibody
Anti-PPP2R2A antibody (ab18136)参考文献
This product has been referenced in:
et al. PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential. Mol Cancer Ther 13:938-47 (2014).
Read more (PubMed: 24448818) »
et al. The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models. Cancer Lett 339:135-43 (2013).
Read more (PubMed: 23887057) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"