概述

  • 产品名称Anti-PPP2CB抗体
    参阅全部 PPP2CB 一抗
  • 描述
    兔多克隆抗体to PPP2CB
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to to a region within C-terminal amino acids 277-307 of Human PPP2CB (NP_001009552.1).

  • 阳性对照
    • T47D cell line lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab116324 is purified through a Protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab116324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 36 kDa.

靶标

  • 功能PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
  • 序列相似性Belongs to the PPP phosphatase family. PP-1 subfamily.
  • 翻译后修饰Reversibly methyl esterified on Leu-309. Carboxyl methylation may play a role in holoenzyme assembly. It varies during the cell cycle. Demethylated by PME1 (in vitro).
    Phosphorylation of either threonine (by autophosphorylation-activated protein kinase) or tyrosine results in inactivation of the phosphatase. Auto-dephosphorylation has been suggested as a mechanism for reactivation.
  • 细胞定位Cytoplasm. Nucleus. Chromosome > centromere. Cytoplasm > cytoskeleton > spindle pole. In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PP2A beta antibody
    • PP2A-beta antibody
    • PP2AB_HUMAN antibody
    • PP2Abeta antibody
    • PP2CB antibody
    • Ppp2cb antibody
    • Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody
    • Protein phosphatase 2 catalytic subunit beta isozyme antibody
    • Protein phosphatase 2, catalytic subunit, beta isoform antibody
    • Protein phosphatase 2A catalytic subunit beta isoform antibody
    • Protein phosphatase type 2A catalytic subunit antibody
    • Serine/threonine protein phosphatase 2A catalytic subunit beta antibody
    • Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody
    see all

Anti-PPP2CB antibody 图像

  • Anti-PPP2CB antibody (ab116324) at 1/100 dilution + T47D cell line lysate at 35 µg

    Predicted band size : 36 kDa

Anti-PPP2CB antibody (ab116324)参考文献

ab116324 has not yet been referenced specifically in any publications.

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