概述

  • 产品名称Anti-PPP1R3D抗体
  • 描述
    兔多克隆抗体to PPP1R3D
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen: ELAQVKVFNA GDDPSVPLHV LSRLAINSDL CCSSQDLEFT LHCLVPDFPP PVEAADFGER LQRQLVCLER VTCSDL, corresponding to amino acids 112-187 of Human PPP1R3D (O95685).

  • 阳性对照
    • Human rectum tissue

性能

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应用

Our Abpromise guarantee covers the use of ab122696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 功能Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.
  • 组织特异性Expressed in all tissue tested. High expression in skeletal muscle and heart.
  • 序列相似性Contains 1 CBM21 (carbohydrate binding type-21) domain.
  • 结构域The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PP1 subunit R6 antibody
    • PPP1R3D antibody
    • PPP1R6 antibody
    • PPR3D_HUMAN antibody
    • Protein phosphatase 1 regulatory subunit 3D antibody
    • Protein phosphatase 1 regulatory subunit 6 antibody
    • Protein phosphatase 1-binding subunit R6 antibody
    see all

Anti-PPP1R3D antibody 图像

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleoli, cytoplasm and mitochondria. Recommended concentration of ab122696 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122696, at 1/200 dilution, staining PPP1R3D in Paraffin-embedded Human rectum tissue by Immunohistochemistry

Anti-PPP1R3D antibody (ab122696)参考文献

ab122696 has not yet been referenced specifically in any publications.

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