概述

  • 产品名称Anti-PPP1R3A抗体
    参阅全部 PPP1R3A 一抗
  • 描述
    兔多克隆抗体to PPP1R3A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 757-786 of Human PPP1R3A (NP_002702.2).

  • 阳性对照
    • Jurkat cell line lysates

性能

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应用

Our Abpromise guarantee covers the use of ab107367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 126 kDa.

靶标

  • 功能Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
  • 组织特异性Skeletal muscle and heart.
  • 疾病相关Diabetes mellitus, non-insulin-dependent
  • 序列相似性Contains 1 CBM21 (carbohydrate binding type-21) domain.
  • 结构域The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
  • 翻译后修饰Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody
    • Glycogen associated regulatory subunit of protein phosphatase 1 antibody
    • GM antibody
    • PP1G antibody
    • PPP1R3 antibody
    • PPP1R3A antibody
    • PPR3A_HUMAN antibody
    • Protein phosphatase 1 glycogen-associated regulatory subunit antibody
    • Protein phosphatase 1 glycogen-targeting subunit, muscle antibody
    • Protein phosphatase 1 regulatory subunit 3A antibody
    • Protein phosphatase 1 regulatory subunit GM antibody
    • protein phosphatase 1, regulatory (inhibitor) subunit 3A antibody
    • Protein phosphatase 1, regulatory subunit 3 antibody
    • Protein phosphatase type-1 glycogen targeting subunit antibody
    • RG1 antibody
    • Serine /threonine specific protein phosphatase antibody
    • Type 1 protein phosphatase skeletal muscle glycogen targeting subunit antibody
    see all

Anti-PPP1R3A antibody 图像

  • Anti-PPP1R3A antibody (ab107367) at 1/100 dilution + Jurkat cell line lysates at 35 µg

    Predicted band size : 126 kDa

Anti-PPP1R3A antibody (ab107367)参考文献

ab107367 has not yet been referenced specifically in any publications.

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