产品名称 Anti-PPP1R3A抗体 参阅全部 PPP1R3A 一抗
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Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 757-786 of Human PPP1R3A (NP_002702.2).
存放说明 Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
存储溶液 Preservative: 0.09% Sodium Azide
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纯度 Immunogen affinity purified
纯化说明 This antibody is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 126 kDa.
功能 Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
组织特异性 Skeletal muscle and heart.
疾病相关 Diabetes mellitus, non-insulin-dependent
序列相似性 Contains 1 CBM21 (carbohydrate binding type-21) domain.
结构域 The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
翻译后修饰 Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
Information by UniProt
Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody
Glycogen associated regulatory subunit of protein phosphatase 1 antibody
Anti-PPP1R3A antibody (ab107367)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"