概述

  • 产品名称Anti-PPFIA4抗体
    参阅全部 PPFIA4 一抗
  • 描述
    小鼠单克隆抗体to PPFIA4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: RQVMEREFNN LLALGTDRKL DDGDDKVFRR APSWRKRFRP REHHGRGGML SASAETLPAG FRVSTLGTLQ PPPAPPKKIM PEAHSHYLYG HMLSAF, corresponding to amino acids 604-700 of Human PPFIA4

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
    • 组织特异性Expressed only in the heart, brain, and skeletal muscle.
    • 序列相似性Belongs to the liprin family. Liprin-alpha subfamily.
      Contains 3 SAM (sterile alpha motif) domains.
    • 结构域The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.
    • 细胞定位Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
    • Information by UniProt
    • 数据库链接
    • 别名
      • KIAA0897 antibody
      • LIPA4_HUMAN antibody
      • Liprin alpha 4 antibody
      • Liprin-alpha-4 antibody
      • PPFIA 4 antibody
      • PPFIA4 antibody
      • Protein tyrosine phosphatase receptor type f polypeptide (PTPRF) interacting protein (liprin) alpha 4 antibody
      • Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 4 antibody
      • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4 antibody
      • PTPRF interacting protein alpha 4 antibody
      • PTPRF-interacting protein alpha-4 antibody
      see all

    Anti-PPFIA4 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56339 PPFIA4 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-PPFIA4 antibody (ab56339)参考文献

    This product has been referenced in:
    • Kiok K  et al. Liprin-a4 Is Required for Nickel Induced Receptor Protein Tyrosine Phosphatase-Leukocyte Antigen Related Receptor F (RPTP-LAR) Activity. PLoS One 6:e22764 (2011). WB ; Human . Read more (PubMed: 21829649) »

    See 1 Publication for this product

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