概述

  • 产品名称Anti-PPAR delta抗体
    参阅全部 PPAR delta 一抗
  • 描述
    山羊多克隆抗体to PPAR delta
  • 特异性ab21209 recognises isoform 1 of PPAR delta, but not isoform 2, a shorter protein with a different C-terminus.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Cow, Pig
  • 免疫原

    Synthetic peptide:

    CHPLLQEIYKDMY

    , corresponding to C terminal amino acids 429-441 of Human PPAR delta .

  • 阳性对照
    • Jurkat cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab21209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/16000.
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 50 kDa).

靶标

  • 功能Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
  • 组织特异性Ubiquitous with maximal levels in placenta and skeletal muscle.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FAAR antibody
    • MGC3931 antibody
    • NR1C2 antibody
    • NUC1 antibody
    • NUCI antibody
    • NUCII antibody
    • Nuclear hormone receptor 1 antibody
    • Nuclear receptor subfamily 1 group C member 2 antibody
    • Peroxisome proliferative activated receptor delta antibody
    • Peroxisome proliferator-activated receptor beta (PPAR-beta) antibody
    • Peroxisome proliferator-activated receptor beta antibody
    • Peroxisome proliferator-activated receptor delta antibody
    • PPAR beta antibody
    • PPAR-beta antibody
    • PPAR-delta antibody
    • PPAR-ß antibody
    • PPARB antibody
    • ppard antibody
    • PPARD_HUMAN antibody
    see all

Anti-PPAR delta antibody 图像

  • Anti-PPAR delta antibody (ab21209) + Jurkat lysate (35µg protein in RIPA buffer).

    Performed under reducing conditions.

    Predicted band size : 50 kDa
    Observed band size : 50 kDa

Anti-PPAR delta antibody (ab21209)参考文献

This product has been referenced in:
  • Borland MG  et al. Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor ß/d (PPARß/d) in keratinocytes. Carcinogenesis N/A:N/A (2014). Read more (PubMed: 24639079) »
  • Borland MG  et al. Stable over-expression of PPARß/d and PPAR? to examine receptor signaling in human HaCaT keratinocytes. Cell Signal 23:2039-50 (2011). WB ; Human . Read more (PubMed: 21843636) »

See all 3 Publications for this product

Product Wall

Application Western blot
Sample Mouse Cell lysate - whole cell (thymus)
Loading amount 20 µg
Specification thymus
Gel Running Conditions Reduced Denaturing (12 %)
Blocking step BSA as blocking agent for 36 hour(s) and 0 minute(s) · Concentration: 2% · Temperature: 4°C
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提交于 Mar 17 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"