概述

  • 产品名称Anti-PON2抗体
    参阅全部 PON2 一抗
  • 描述
    山羊多克隆抗体to PON2
  • 特异性This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Dog, Pig
  • 免疫原

    Synthetic peptide:

    EKPRARELRIS

    by a Cysteine residue linker, corresponding to internal sequence amino acids 93-103 of Human PON2 (NP_000296.2; NP_001018171.1)

  • 阳性对照
    • HepG2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab99550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 0.6 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 39 kDa).

靶标

  • 功能Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
  • 组织特异性Widely expressed with highest expression in liver, lung, placenta, testis and heart.
  • 序列相似性Belongs to the paraoxonase family.
  • 翻译后修饰The signal sequence is not cleaved.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A esterase 2 antibody
    • A-esterase 2 antibody
    • Aromatic esterase 2 antibody
    • Paraoxonase 2 antibody
    • Paraoxonase nirs antibody
    • PON 2 antibody
    • PON2 antibody
    • PON2_HUMAN antibody
    • Serum aryldialkylphosphatase 2 antibody
    • Serum paraoxonase/arylesterase 2 antibody
    see all

Anti-PON2 antibody 图像

  • Anti-PON2 antibody (ab99550) at 1 µg/ml (incubation time 1 hour) + HepG2 cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

Anti-PON2 antibody (ab99550)参考文献

ab99550 has not yet been referenced specifically in any publications.

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