概述

  • 产品名称Anti-POMT2抗体
    参阅全部 POMT2 一抗
  • 描述
    兔多克隆抗体to POMT2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    A synthetic peptide corresponding to a region of Human POMT2 (NP_037514)

  • 阳性对照
    • HeLa cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab76396 is purified by a peptide affinity chromatography method.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab76396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 84 kDa (predicted molecular weight: 84 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.

靶标

  • 功能Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.
  • 组织特异性Highly expressed in testis; detected at low levels in most tissues.
  • 通路Protein modification; protein glycosylation.
  • 疾病相关Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A2 (MDDGA2) [MIM:613150]: An autosomal recessive disorder characterized by congenital muscular dystrophy associated with cobblestone lissencephaly and other brain anomalies, eye malformations, profound mental retardation, and death usually in the first years of life. Included diseases are the more severe Walker-Warburg syndrome and the slightly less severe muscle-eye-brain disease. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Muscular dystrophy-dystroglycanopathy congenital with mental retardation B2 (MDDGB2) [MIM:613156]: An autosomal recessive disorder characterized by congenital muscular dystrophy associated with mental retardation and mild structural brain abnormalities. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Muscular dystrophy-dystroglycanopathy limb-girdle C2 (MDDGC2) [MIM:613158]: An autosomal recessive muscular dystrophy with onset after ambulation is achieved. MDDGC2 is characterized by increased serum creatine kinase and mild muscle weakness. Muscle biopsy shows dystrophic changes, inflammatory changes, and severely decreased alpha-dystroglycan. Cognition is normal. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 序列相似性Belongs to the glycosyltransferase 39 family.
    Contains 3 MIR domains.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A830009D15Rik antibody
    • AW046274 antibody
    • DKFZp686G10254 antibody
    • Dolichyl phosphate mannose protein mannosyltransferase 2 antibody
    • Dolichyl-phosphate-mannose--protein mannosyltransferase 2 antibody
    • FLJ22309 antibody
    • LGMD2N antibody
    • MDDGA2 antibody
    • MDDGB2 antibody
    • MDDGC2 antibody
    • POMT 2 antibody
    • Pomt2 antibody
    • POMT2_HUMAN antibody
    • Protein O mannosyltransferase 2 antibody
    • Protein O mannosyltransferase antibody
    • Protein O-mannosyl-transferase 2 antibody
    • Putative protein O mannosyltransferase antibody
    • rCG_20643 antibody
    see all

Anti-POMT2 antibody 图像

  • Anti-POMT2 antibody (ab76396) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 84 kDa
    Observed band size : 84 kDa

Anti-POMT2 antibody (ab76396)参考文献

ab76396 has not yet been referenced specifically in any publications.

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