Anti-RPC39抗体(ab76951)
Key features and details
- Rabbit polyclonal to RPC39
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-RPC39抗体
参阅全部 RPC39 一抗 -
描述
兔多克隆抗体to RPC39 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human RPC39 (N terminal).
-
阳性对照
- Human brain tissue lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76951于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 36 kDa.
|
|
ICC/IF |
Use a concentration of 20 µg/ml.
|
|
IHC-P |
Use a concentration of 2.5 µg/ml.
|
说明 |
---|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 36 kDa. |
ICC/IF
Use a concentration of 20 µg/ml. |
IHC-P
Use a concentration of 2.5 µg/ml. |
靶标
-
功能
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. -
序列相似性
Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 10621 Human
- SwissProt: Q9H1D9 Human
- Unigene: 472227 Human
-
别名
- DNA directed RNA polymerase III 39 kDa polypeptide antibody
- DNA directed RNA polymerase III 39 kDa polypeptide F antibody
- DNA directed RNA polymerase III subunit F antibody
see all
图片
-
Immunofluorescence of RPC39 in Human brain tissue with ab76951 at 20 ug/mL.
-
Lane 1 : Anti-RPC39 antibody (ab76951) at 0.5 µg/ml
Lane 2 : Anti-RPC39 antibody (ab76951) at 1 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 36 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted? -
ab76951 at 2.5µg/ml staining RPC39 in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab76951 尚未被引用在任何文献中。