概述

  • 产品名称Anti-POLR2G抗体
    参阅全部 POLR2G 一抗
  • 描述
    兔多克隆抗体to POLR2G
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Zebrafish
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1 and 142 of POLR2G (NP_002687).

  • 阳性对照
    • WB: 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates IHC-P: CL1-5 xenograft

性能

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应用

Our Abpromise guarantee covers the use of ab96031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 19 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.
  • 序列相似性Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DNA directed RNA polymerase II 19 kDa polypeptide antibody
    • DNA directed RNA polymerase II subunit G antibody
    • DNA directed RNA polymerase II subunit RPB7 antibody
    • DNA-directed RNA polymerase II subunit G antibody
    • DNA-directed RNA polymerase II subunit RPB7 antibody
    • hRPB19 antibody
    • hsRPB7 antibody
    • MGC138367 antibody
    • MGC138369 antibody
    • POLR2G antibody
    • polymerase (RNA) II (DNA directed) polypeptide G antibody
    • RNA polymerase II 19 kDa subunit antibody
    • RNA polymerase II subunit B7 antibody
    • RPB19 antibody
    • RPB7 antibody
    • RPB7_HUMAN antibody
    see all

Anti-POLR2G antibody 图像

  • Anti-POLR2G antibody (ab96031) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 19 kDa
  • Immunohistochemical analysis of POLR2G in paraffin embedded CL1-5 xenograft, using ab96031 at a 1/500 dilution.

Anti-POLR2G antibody (ab96031)参考文献

ab96031 has not yet been referenced specifically in any publications.

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