概述

  • 产品名称Anti-POLR2E抗体
    参阅全部 POLR2E 一抗
  • 描述
    兔多克隆抗体to POLR2E
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 29-59 of Human POLR2E (NP_002686.2).

  • 阳性对照
    • A549 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab123284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 25 kDa.

靶标

  • 功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
  • 序列相似性Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • and III subunit ABC1 antibody
    • and III subunit RPABC1 antibody
    • DNA directed RNA polymerase II 23 kda polypeptide antibody
    • DNA directed RNA polymerase II 23 kDa polypeptide antibody
    • DNA directed RNA polymerase II polypeptide E antibody
    • DNA directed RNA polymerase II subunit E antibody
    • DNA directed RNA polymerases I II and III subunit RPABC1 antibody
    • DNA-directed RNA polymerase II 23 kDa polypeptide antibody
    • DNA-directed RNA polymerase II subunit E antibody
    • DNA-directed RNA polymerases I antibody
    • hRPB25 antibody
    • hsRPB5 antibody
    • II antibody
    • Polr2e antibody
    • Polymerase (RNA) II (DNA directed) polypeptide E (25kD) antibody
    • Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa antibody
    • RNA polymerases I antibody
    • RNA polymerases I, II, and III subunit ABC1 antibody
    • RPAB1_HUMAN antibody
    • RPABC1 antibody
    • RPB5 antibody
    • RPB5 homolog antibody
    • XAP4 antibody
    see all

Anti-POLR2E antibody 图像

  • Anti-POLR2E antibody (ab123284) at 1/100 dilution + A549 cell line lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 25 kDa

Anti-POLR2E antibody (ab123284)参考文献

ab123284 has not yet been referenced specifically in any publications.

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