Anti-Poliovirus Receptor抗体(ab103630)


  • 产品名称Anti-Poliovirus Receptor抗体
    参阅全部 Poliovirus Receptor 一抗
  • 描述
    兔多克隆抗体to Poliovirus Receptor
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-417 of Human Poliovirus Receptor (NP_006496.2).

  • 阳性对照
    • Mouse stomach tissue lysate.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab103630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
ICC/IF 1/200.


  • 功能Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.
  • 序列相似性Belongs to the nectin family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD155 antibody
    • CD155 antigen antibody
    • FLJ25946 antibody
    • HVED antibody
    • mE4 antibody
    • NECL 5 antibody
    • Necl-5 antibody
    • Necl5 antibody
    • Nectin like 5 antibody
    • Nectin like protein 5 antibody
    • Nectin-like protein 5 antibody
    • Ortholog of mouse Tage4 antibody
    • Poliovirus receptor antibody
    • PVR antibody
    • PVR_HUMAN antibody
    • PVS antibody
    • Taa1 antibody
    • Tage 4 antibody
    • TAGE4 antibody
    see all

Anti-Poliovirus Receptor antibody 图像

  • Anti-Poliovirus Receptor antibody (ab103630) at 1/500 dilution + Mouse stomach tissue lysate at 50 µg

    Predicted band size : 45 kDa
  • All lanes : Anti-Poliovirus Receptor antibody (ab103630) at 1/500 dilution

    Lane 1 : Poliovirus Receptor transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 45 kDa
  • Immunofluorescence analysis of murine stomach, staining Poliovirus Receptor with ab103630.

    Cells were fixed with acetone and blocked with 1% BSA for 30 minutes at 25°C. Samples were incubated with primary antibody (1/200 in diluent) for 24 hours at 4°C. A Cy3®-conjugated sheep anti-rabbit polyclonal IgG (1/3000) was used as the secondary antibody.

    See Abreview

Anti-Poliovirus Receptor antibody (ab103630)参考文献

ab103630 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 35 µg
Gel Running Conditions Reduced Denaturing
Sample Pig Cell lysate - whole cell (Swine kidney)
Specification Swine kidney
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C

Korneel Grauwet

Verified customer

提交于 Oct 07 2013

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Mouse Cell (Stomach)
Specification Stomach
Fixative Acetone
Permeabilization No
Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: 25°C

Abcam user community

Verified customer

提交于 Oct 18 2012


Expiration date: 27/12/2012

I am very pleased to hear you would like to accept our offer and testab103630 in IHC-Fr on Ms stomack. This code will give you: 1 free PRIMARY ANTIBODY/PROTEIN OR VALUE OFF OF O...

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Thank you for your answer.

It is very important to design a good control experiments when two untested factors are involved. Could you please confirm ifyou are going to useformalin-fixed paraffin-embedded(IHC-P) or frozen tissue (IHC-Fr) sect...

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Thank you for getting back to me.

This antibody has only been tested in Western blot application on tissue lysate of mouse stomach and transfected human cells (293T). It is very important to control the testing experiments to make sure that t...

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Thank you for your enquiry and your interest in our products.

This antibody (ab103630: Anti-Poliovirus Receptor antibody) has not been tested in rat neither in immunohistochemistry.

We can offer testing discount only for either new ...

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