概述

  • 产品名称Anti-PNRC2抗体
    参阅全部 PNRC2 一抗
  • 描述
    兔多克隆抗体to PNRC2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide, corresponding to N terminal amino acids 1-50 (MGGGERYNIP DPQSRNASKN QQQHNRQKTK DQNSQMKIVH KKKERGHGYN) of Rat PNRC2 (NP_001096830).

  • 阳性对照
    • Rat kidney lysate

性能

应用

Our Abpromise guarantee covers the use of ab113834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 15 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.
  • 组织特异性Expressed in heart, lung, muscle and brain.
  • 序列相似性Belongs to the PNRC family. PNRC2 subfamily.
  • 结构域The interaction between PNRC2 and nuclear receptors is dependent on the SH3 binding motif.
  • 细胞定位Nucleus. Cytoplasm > P-body.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 0610011E17Rik antibody
    • D4Bwg0593e antibody
    • FLJ20312 antibody
    • MGC11707 antibody
    • MGC93828 antibody
    • MGC99541 antibody
    • OTTMUSP00000010360 antibody
    • OTTMUSP00000010366 antibody
    • pnrc2 antibody
    • PNRC2_HUMAN antibody
    • Proline rich nuclear receptor coactivator 2 antibody
    • Proline-rich nuclear receptor coactivator 2 antibody
    • RP11-4M23.5 antibody
    • RP23-161N17.3 antibody
    see all

Anti-PNRC2 antibody 图像

  • Anti-PNRC2 antibody (ab113834) at 1 µg/ml + Rat kidney lysate at 10 µg

    Predicted band size : 15 kDa

Anti-PNRC2 antibody (ab113834)参考文献

ab113834 has not yet been referenced specifically in any publications.

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