Anti-Pneumolysin抗体(ab71811)
Key features and details
- Rabbit polyclonal to Pneumolysin
- Suitable for: WB
- Isotype: IgG
概述
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产品名称
Anti-Pneumolysin抗体
参阅全部 Pneumolysin 一抗 -
描述
兔多克隆抗体to Pneumolysin -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Streptococcus pneumoniae -
免疫原
Recombinant full length protein
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.50
Constituent: 0.06% Tris buffered saline -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab71811于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (1) |
Use at an assay dependent dilution.
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说明 |
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WB
Use at an assay dependent dilution. |
靶标
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细胞定位
Plasma membrane -
数据库链接
- SwissProt: P0C2J9 Streptococcus pneumoniae
数据表及文件
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SDS download
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Datasheet download
文献 (9)
ab71811 被引用在 9 文献中.
- Jacques LC et al. Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin. Nat Commun 11:1892 (2020). PubMed: 32312961
- Panagiotou S et al. Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity. Sci Rep 10:17313 (2020). PubMed: 33057054
- Badgujar DC et al. Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle. PLoS Pathog 16:e1009016 (2020). PubMed: 33216805
- Subramanian K et al. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nat Microbiol 4:62-70 (2019). PubMed: 30420782
- Ye J et al. First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae. Molecules 24:N/A (2019). PubMed: 31405060
- Surve MV et al. Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking. PLoS Pathog 14:e1007168 (2018). PubMed: 30011336
- Shenoy AT et al. Severity and properties of cardiac damage caused by Streptococcus pneumoniae are strain dependent. PLoS One 13:e0204032 (2018). PubMed: 30216364
- Liu EY et al. Differences in virulence of pneumolysin and autolysin mutants constructed by insertion duplication mutagenesis and in-frame deletion in Streptococcus pneumoniae. BMC Biotechnol 14:16 (2014). WB . PubMed: 24558977
- Brown AO et al. Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function. PLoS Pathog 10:e1004383 (2014). IHC-P, IHC-Fr . PubMed: 25232870