PLTP Inhibitor Drug Screening试剂盒(ab65387)

概述

  • 产品名称PLTP Inhibitor Drug Screening试剂盒
    参阅全部 Plasma phospholipid transfer protein 试剂盒
  • 测试
    100 x 1 assay
  • 样品类型
    Cell culture supernatant, Milk, Urine, Serum, Plasma, Other biological fluids, Tissue Extracts
  • 检测类型Quantitative
  • 检测时间
    0h 40m
  • 产品概述

    Abcam's PLTP Drug Screening Kit utilizes rabbit serum as PLTP activity source to screen PLTP inhibitors. The assay uses a donor molecule containing a fluorescent self-quenched phospholipid that is transferred to an acceptor molecule in the presence of PLTP. PLTP-mediated transfer of the fluorescent phospholipid to the acceptor molecule results in an increase in fluorescence (Ex/ Em- 465/ 535 nm). Inhibitor of PLTP will inhibit the lipid transfer and therefore decrease fluorescence intensity. The kit provides sufficient reagents for 100 PLTP inhibitor screening assays.
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  • 说明

    Plasma phospholipid transfer protein (PLTP) is thought to play a major role in the facilitated transfer of phospholipids between lipoproteins and in the modulation of high-density lipoprotein (HDL) particle size and composition. PLTP-facilitated lipid transfer activity is related to HDL and LDL metabolism, as well as lipoprotein lipase activity, adiposity, and insulin resistance.

  • 经测试应用适用于: Functional Studiesmore details

性能

  • 相关性Plasma phospholipid transfer protein (PLTP) is thought to play a major role in the facilitated transfer of phospholipids between lipoproteins and in the modulation of high-density lipoprotein (HDL) particle size and composition. PLTP-facilitated lipid transfer activity is related to HDL and LDL metabolism, as well as lipoprotein lipase activity, adiposity, and insulin resistance.
  • 细胞定位Secreted.
  • 别名
    • HDLCQ9
    • Lipid transfer protein II
    • Phospholipid transfer protein
    • PLTP

应用

Our Abpromise guarantee covers the use of ab65387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Functional Studies Use at an assay dependent dilution.

实验方案

PLTP Inhibitor Drug Screening Kit (ab65387)参考文献

ab65387 has not yet been referenced specifically in any publications.

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