概述

  • 产品名称Anti-PLTP抗体
    参阅全部 PLTP 一抗
  • 描述
    兔多克隆抗体to PLTP
  • 经测试应用适用于: IHC-Fr, ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant full length protein (Human)

应用

Our Abpromise guarantee covers the use of ab18990 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/50.
ICC/IF Use a concentration of 1 - 10 µg/ml.
WB 1/500. Predicted molecular weight: 55 kDa.

靶标

  • 功能Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles.
  • 组织特异性Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.
  • 序列相似性Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BPI fold containing family E antibody
    • BPIFE antibody
    • HDLCQ9 antibody
    • High density lipoprotein cholesterol level quantitative trait locus 9, included antibody
    • Lipid transfer protein II antibody
    • OD107 antibody
    • Phospholipid transfer protein antibody
    • Plasma phospholipid transfer protein antibody
    • Pltp antibody
    • PLTP_HUMAN antibody
    see all

Anti-PLTP antibody 图像

  • ICC/IF image of ab18990 stained HeLa cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab18990, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-PLTP antibody (ab18990)参考文献

This product has been referenced in:
  • Chenau J  et al. The cell line secretome, a suitable tool for investigating proteins released in vivo by tumors: application to the study of p53-modulated proteins secreted in lung cancer cells. J Proteome Res 8:4579-91 (2009). WB ; Human . Read more (PubMed: 19639960) »
  • Desrumaux CM  et al. Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells. J Lipid Res 44:1453-61 (2003). IHC-P ; Human . Read more (PubMed: 12730304) »

See all 2 Publications for this product

Product Wall

Thank you for contacting Abcam.

The only western blot images that we have for ab18990 are those that are found in the following reference, PubMed: 19639960.

Also, we have not tested this antibody in whole mount sections and so we ca...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"