概述

  • 产品名称
  • 描述
    兔多克隆抗体to PLK3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 32-61 of Mouse PLK3 (Q60806).

  • 阳性对照
    • WiDr cell line lysates and Neuro-2a cell line lysates.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab123695 was purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 70 kDa.

靶标

  • 功能
    Serine/threonine protein kinase involved in regulating M phase functions during the cell cycle. May also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein.
  • 组织特异性
    Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. May have a short half-live. In cells of hematopoietic origin, strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor.
  • 序列相似性
    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
    Contains 2 POLO box domains.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CNK antibody
    • Cytokine Inducible Kinase antibody
    • Cytokine-inducible serine/threonine-protein kinase antibody
    • FGF inducible kinase antibody
    • FGF-inducible kinase antibody
    • FNK antibody
    • PLK-3 antibody
    • Plk3 antibody
    • PLK3_HUMAN antibody
    • Polo Like Kinase 3 antibody
    • Polo-like kinase 3 antibody
    • PRK antibody
    • Proliferation Related Kinase antibody
    • Proliferation-related kinase antibody
    • Serine/threonine-protein kinase PLK3 antibody
    see all

Anti-PLK3 antibody 图像

  • Anti-PLK3 antibody (ab123695) at 1/100 dilution + WiDr cell line lysates at 35 µg

    Predicted band size : 70 kDa
  • Anti-PLK3 antibody (ab123695) at 1/100 dilution + Neuro-2a cell line lysates at 35 µg

    Predicted band size : 70 kDa

实验方案

Anti-PLK3 antibody (ab123695)参考文献

ab123695 has not yet been referenced specifically in any publications.

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