Anti-PLK3抗体(ab113639)

概述

  • 产品名称Anti-PLK3抗体
    参阅全部 PLK3 一抗
  • 描述
    兔多克隆抗体to PLK3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal amino acids 358-434 (PDVRPEAPVV SGQAPASLVE TAAEDSSPRG TLASSGDGFE EGLTVATVVE) of Mouse PLK3 (NP_038835).

  • 阳性对照
    • Mouse Brain Lysate

性能

应用

Our Abpromise guarantee covers the use of ab113639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 72 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Serine/threonine protein kinase involved in regulating M phase functions during the cell cycle. May also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein.
  • 组织特异性Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. May have a short half-live. In cells of hematopoietic origin, strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor.
  • 序列相似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
    Contains 2 POLO box domains.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CNK antibody
    • Cytokine Inducible Kinase antibody
    • Cytokine-inducible serine/threonine-protein kinase antibody
    • FGF inducible kinase antibody
    • FGF-inducible kinase antibody
    • FNK antibody
    • PLK-3 antibody
    • Plk3 antibody
    • PLK3_HUMAN antibody
    • Polo Like Kinase 3 antibody
    • Polo-like kinase 3 antibody
    • PRK antibody
    • Proliferation Related Kinase antibody
    • Proliferation-related kinase antibody
    • Serine/threonine-protein kinase PLK3 antibody
    see all

Anti-PLK3 antibody 图像

  • Anti-PLK3 antibody (ab113639) at 1 µg/ml + Mouse Brain Lysate at 10 µg

    Predicted band size : 72 kDa

Anti-PLK3 antibody (ab113639)参考文献

ab113639 has not yet been referenced specifically in any publications.

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