概述

  • 产品名称Anti-PLCL1抗体
    参阅全部 PLCL1 一抗
  • 描述
    兔多克隆抗体to PLCL1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the N terminal region of Human PLCL1 (NP_006217.2)

  • 阳性对照
    • Jurkat cell line lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明This antibody is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab93425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 123 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
    • 组织特异性Expressed in a variety of fetal and adult organs including brain, lung and kidney. Its expression was greatly reduced in small and non-small cell lung carcinoma. Isoform 1 is predominantly expressed in brain.
    • 序列相似性Contains 1 C2 domain.
      Contains 1 PH domain.
      Contains 1 PI-PLC X-box domain.
      Contains 1 PI-PLC Y-box domain.
    • 翻译后修饰Phosphorylated by the catalytic subunit of PKA. Phosphorylation of Thr-93 resulted in dissociation of PPP1C from PRIP1.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Inactive phospholipase C-like protein 1 antibody
      • Inactive protein 1 antibody
      • Phospholipase C deleted in lung carcinoma antibody
      • Phospholipase C epsilon antibody
      • Phospholipase C like 1 antibody
      • Phospholipase C related but catalytically inactive protein antibody
      • Phospholipase C related, but catalytically inactive protein antibody
      • Phospholipase C-deleted in lung carcinoma antibody
      • Phospholipase C-related but catalytically inactive protein antibody
      • Phospholipase C-related catalytically antibody
      • PLC-L1 antibody
      • PLCE antibody
      • PLCL antibody
      • PLCL1 antibody
      • PLCL1_HUMAN antibody
      • PLDL1 antibody
      • PRIP antibody
      see all

    Anti-PLCL1 antibody 图像

    • Anti-PLCL1 antibody (ab93425) at 1/100 dilution + Jurkat cell line lysates at 35 µg

      Predicted band size : 123 kDa

    Anti-PLCL1 antibody (ab93425)参考文献

    ab93425 has not yet been referenced specifically in any publications.

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