产品名称 Anti-PLC-delta-3抗体 参阅全部 PLC-delta-3 一抗
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Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 59-89 of Human PLC-delta-3 (NP_588614.1).
Mouse liver tissue lysates.
存放说明 Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
存储溶液 Preservative: 0.09% Sodium azide Constituent: 99% PBS
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纯度 Immunogen affinity purified
纯化说明 ab123668 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 89 kDa.
功能 Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.
组织特异性 Present in corneal epithelial cells (at protein level).
序列相似性 Contains 1 C2 domain. Contains 3 EF-hand domains. Contains 1 PH domain. Contains 1 PI-PLC X-box domain. Contains 1 PI-PLC Y-box domain.
结构域 The C2 domain is a Ca(2+)-dependent membrane-targeting module. The PH domain mediates interaction with the surface membrane by binding to PIP2.
细胞定位 Membrane. Cytoplasm. Cleavage furrow. Localizes at the cleavage furrow during cytokinesis.
Information by UniProt
5-bisphosphate phosphodiesterase delta-3 antibody
Phosphoinositide phospholipase C-delta-3 antibody
Anti-PLC-delta-3 antibody 图像
Anti-PLC-delta-3 antibody (ab123668)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"