Anti-Plasma Kallikrein 1B抗体(ab75228)


  • 产品名称Anti-Plasma Kallikrein 1B抗体
    参阅全部 Plasma Kallikrein 1B 一抗
  • 描述
    兔多克隆抗体to Plasma Kallikrein 1B
  • 特异性ab75228 detects endogenous levels of fragment of activated Plasma Kallikrein 1B heavy chain resulting from cleavage adjacent to Arg390.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from human plasma Kallikrein 1B.

  • 阳性对照
    • Extracts from HeLa cells.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab75228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
ELISA 1/10000.


  • 功能The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
  • 疾病相关Defects in KLKB1 are the cause of prekallikrein deficiency (PKK deficiency) [MIM:612423]; also known as Fletcher factor deficiency. This disorder is a blood coagulation defect.
  • 序列相似性Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
    Contains 4 apple domains.
    Contains 1 peptidase S1 domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Fletcher factor antibody
    • kallikrein B plasma antibody
    • Kallikrein B plasma (Fletcher factor) 1 antibody
    • Kallikrein B, plasma 1 antibody
    • Kininogenin antibody
    • KLK3 antibody
    • KLKB1 antibody
    • KLKB1_HUMAN antibody
    • Plasma kallikrein antibody
    • Plasma kallikrein B1 antibody
    • Plasma kallikrein light chain antibody
    • Plasma prekallikrein antibody
    • PPK antibody
    • Prekallikrein antibody
    see all

Anti-Plasma Kallikrein 1B antibody 图像

  • All lanes : Anti-Plasma Kallikrein 1B antibody (ab75228) at 1/500 dilution

    Lane 1 : Extracts from HeLa cells
    Lane 2 : Extracts from HeLa cells with Cl peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 45 kDa
    Observed band size : 45 kDa

Anti-Plasma Kallikrein 1B antibody (ab75228)参考文献

ab75228 has not yet been referenced specifically in any publications.

Product Wall

I will send the alignment results for ab116517, hopefully later today.

I am glad ab1006 is working, at least with human samples. If you have time, we encourage our customers to send us reviews of their results, positive or negative, via our ...

Read More

This is frustrating for us too, finding incorrect information on our datasheets. We try to minimize it but there is clearly work to be done.

I did not realize you had already purchased the antibody. If you would still like to try it with rat...

Read More