Anti-PLAC1抗体(ab105395)
Key features and details
- Rabbit polyclonal to PLAC1
- Suitable for: WB, ICC
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-PLAC1抗体
参阅全部 PLAC1 一抗 -
描述
兔多克隆抗体to PLAC1 -
宿主
Rabbit -
特异性
ab105395 is predicted not to cross-react with other PLAC family protein members. -
经测试应用
适用于: WB, ICCmore details -
种属反应性
与反应: Human -
免疫原
A 15 amino acid synthetic peptide from near the carboxy terminus of Human PLAC1 (NP_068568).
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阳性对照
- Human placenta tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105395于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 24 kDa.
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ICC |
Use a concentration of 10 - 20 µg/ml.
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说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 24 kDa. |
ICC
Use a concentration of 10 - 20 µg/ml. |
靶标
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功能
May play a role in placental development. -
组织特异性
Expressed in placenta. Localizes primarily to differentiated syncytiotrophoblast throughout gestation as well as to a small population of villous cytotrophoblasts. Also detected in maternal blood and rapidly disappears following delivery, but is not detected in other adult or fetal tissues examined. -
序列相似性
Belongs to the PLAC1 family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 10761 Human
- Omim: 300296 Human
- SwissProt: Q9HBJ0 Human
- Unigene: 496811 Human
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别名
- Cancer/testis antigen 92 antibody
- CT92 antibody
- Plac1 antibody
see all
图片
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All lanes : Anti-PLAC1 antibody (ab105395) at 1 µg/ml
Lane 1 : Human placenta tissue lysate
Lane 2 : Human placenta tissue lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 24 kDa -
Immunocytochemistry of PLAC1 in HeLa cells with ab105395 at 10 µg/ml.
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Immunofluorescence of PLAC1 in Hela cells using ab105395 at 20 ug/ml.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab105395 被引用在 5 文献中.
- Sun D et al. PLAC1 Regulates the Occurrence of Fetal Growth Restriction by Inhibiting the Apoptosis of Trophoblast Cells. Ann Clin Lab Sci 51:182-189 (2021). PubMed: 33941557
- Wan L et al. Declined placental PLAC1 expression is involved in preeclampsia. Medicine (Baltimore) 98:e17676 (2019). PubMed: 31689783
- Li Q et al. PLAC1-specific TCR-engineered T cells mediate antigen-specific antitumor effects in breast cancer. Oncol Lett 15:5924-5932 (2018). PubMed: 29556312
- Gormley M et al. Preeclampsia: novel insights from global RNA profiling of trophoblast subpopulations. Am J Obstet Gynecol 217:200.e1-200.e17 (2017). PubMed: 28347715
- Chang WL et al. Role of placenta-specific protein 1 in trophoblast invasion and migration. Reproduction 148:343-52 (2014). PubMed: 24989904