The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa).
功能Contributes to invasiveness in malignant prostate cancer.
组织特异性Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain. Contains 3 REM (Hr1) repeats.
结构域The C1 domain does not bind the diacylglycerol (DAG).
细胞定位Nucleus. Cytoplasm > perinuclear region. Nuclear and perinuclear Golgi region.