存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
存储溶液 PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
纯度 Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明 WB: 1/1000. Detects a band of approximately 105 kDa (predicted molecular weight: 102 kDa).
Is unsuitable for Flow Cyt, IHC or IP.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能 Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
序列相似性 Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily. Contains 1 PH domain. Contains 2 phorbol-ester/DAG-type zinc fingers. Contains 1 protein kinase domain.
细胞定位 Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
Information by UniProt
nPKC D1 antibody
nPKC mu antibody
Anti-PKC mu antibody [EP1493Y] 图像
Western blot - Anti-PKC mu antibody [EP1493Y] (ab51246)
All lanes : Anti-PKC mu antibody [EP1493Y] (ab51246) at 1/1000 dilution Lane 1 : HeLa cell lysate, untreated Lane 2 : HeLa cell lysate, treated with PMA Lysates/proteins at 10 µg per lane. Secondary Goat anti-rabbit HRP labeled at 1/2000 dilution Predicted band size : 102 kDa Observed band size : 105 kDa ( why is the actual band size different from the predicted?)
Anti-PKC mu antibody [EP1493Y] (ab51246)参考文献
This product has been referenced in:
et al. Protein kinase D1 mediates stimulation of DNA synthesis and proliferation in intestinal epithelial IEC-18 cells and in mouse intestinal crypts. J Biol Chem 286:511-20 (2011).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"