概述

  • 产品名称Anti-PKC alpha抗体
    参阅全部 PKC alpha 一抗
  • 描述
    小鼠单克隆抗体to PKC alpha
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 563-673 of Human PKC alpha

性能

应用

Our Abpromise guarantee covers the use of ab57415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 77 kDa.
IHC-P Use a concentration of 1 µg/ml.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4.
    PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
  • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 C2 domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • 细胞定位Cytoplasm. Cell membrane. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAG6 antibody
    • Aging associated gene 6 antibody
    • aPKC antibody
    • KPCA_HUMAN antibody
    • PKC alpha antibody
    • PKC-A antibody
    • PKC-alpha antibody
    • PKCA antibody
    • PRKACA antibody
    • PRKCA antibody
    • Protein Kinase C alpha antibody
    • Protein kinase C alpha type antibody
    see all

Anti-PKC alpha antibody 图像

  • PKC alpha antibody (ab57415) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human tonsil.


  • Predicted band size : 77 kDa
    PKC alpha antibody (ab57415) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • ab57415 at 10 ug/ml staining PKC alpha in human Hella cells by Immunocytochemistry/ Immunofluorescence.

Anti-PKC alpha antibody (ab57415)参考文献

This product has been referenced in:
  • Baldwin AK  et al. Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. J Cell Sci 127:158-71 (2014). WB ; Human . Read more (PubMed: 24190885) »
  • Schober JM  et al. The microtubule-associated protein EB1 maintains cell polarity through activation of protein kinase C. Biochem Biophys Res Commun : (2011). Read more (PubMed: 22120625) »

See all 2 Publications for this product

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