Anti-PKA R2抗体[RS6] (ab10128)

概述

  • 产品名称Anti-PKA R2抗体[RS6]
    参阅全部 PKA R2 一抗
  • 描述
    小鼠单克隆抗体[RS6] to PKA R2
  • 特异性Strongly inhibits holoenzyme formation and cAMP binding.
  • 经测试应用适用于: ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Cow, Human, Pig
  • 免疫原

    Purified regulatory subunit of cAMP-dependent protein kinase type II from bovine brain.

  • 常规说明Concentration varies from lot to lot and can be provided on request.

性能

应用

Our Abpromise guarantee covers the use of ab10128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

靶标

  • 功能Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
  • 组织特异性Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
  • 序列相似性Belongs to the cAMP-dependent kinase regulatory chain family.
    Contains 2 cyclic nucleotide-binding domains.
  • 翻译后修饰Phosphorylated by the activated catalytic chain.
  • 细胞定位Cytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and the cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • cAMP dependent protein kinase regulatory subunit alpha 2 antibody
    • cAMP dependent protein kinase regulatory subunit RII alpha antibody
    • cAMP dependent protein kinase type II alpha regulatory chain antibody
    • cAMP dependent protein kinase type II alpha regulatory subunit antibody
    • cAMP-dependent protein kinase type II-alpha regulatory subunit antibody
    • KAP2 antibody
    • KAP2_HUMAN antibody
    • MGC3606 antibody
    • PKR 2 antibody
    • PKR2 antibody
    • PRKA R2 antibody
    • PRKAR 2 antibody
    • PRKAR2 antibody
    • PRKAR2A antibody
    • Protein kinase A RII alpha subunit antibody
    • Protein kinase cAMP dependent regulatory type II alpha antibody
    see all

Anti-PKA R2 antibody [RS6] (ab10128)参考文献

ab10128 has not yet been referenced specifically in any publications.

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