Anti-PITX1抗体(ab72640)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to PITX1
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal region of human PITX1.

  • 阳性对照
    • Extracts from Jurkat cells and COLO cells.

性能

应用

Our Abpromise guarantee covers the use of ab72640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).
ELISA 1/5000.

靶标

  • 功能
    May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
  • 疾病相关
    Defects in PITX1 are a cause of congenital clubfoot (CCF) [MIM:119800]; also known as talipes equinovarus (TEV). Clubfoot is a congenital limb deformity defined as fixation of the foot in cavus, adductus, varus, and equinus (i.e. inclined inwards, axially rotated outwards, and pointing downwards) with concomitant soft tissue abnormalities. Clubfoot may occur in isolation or as part of a syndrome. Clubfoot appears to be a multifactorial trait.
  • 序列相似性
    Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BFT antibody
    • CCF antibody
    • Hindlimb expressed homeobox protein backfoot antibody
    • Hindlimb-expressed homeobox protein backfoot antibody
    • Homeobox protein PITX1 antibody
    • LBNBG antibody
    • Paired like homeodomain 1 antibody
    • Paired like homeodomain transcription factor 1 antibody
    • Paired-like homeodomain transcription factor 1 antibody
    • Pituitary homeo box 1 antibody
    • Pituitary homeobox 1 antibody
    • Pituitary otx related factor antibody
    • Pitx1 antibody
    • PITX1_HUMAN antibody
    • POTX antibody
    • PTX1 antibody
    see all

Anti-PITX1 antibody 图像

  • All lanes : Anti-PITX1 antibody (ab72640) at 1/500 dilution

    Lane 1 : extracts from Jurkat cells
    Lane 2 : extracts from COLO cells
    Lane 3 : extracts from Jurkat cells, plus immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 34 kDa
    Observed band size : 34 kDa

实验方案

Anti-PITX1 antibody (ab72640)参考文献

ab72640 has not yet been referenced specifically in any publications.

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