Pitstop® 1 - negative control,Negative control for clathrin抑制剂Pitstop® 1 (ab120686)
Key features and details
- Negative control for clathrin inhibitor Pitstop® 1 (ab120685)
- Soluble in DMSO to 100mM and in water to 25mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Pitstop® 1 - negative control,Negative control for clathrin抑制剂Pitstop® 1 -
描述
Negative control for clathrin抑制剂Pitstop® 1 (ab120685) -
生物学描述
Negative control for clathrin inhibitor Pitstop® 1 (ab120685) which is of the same chemical class and has a highly related structure to Pitstop® 1. Inhibits amphiphysin binding to the clathrin TD with an IC50 >100 μM and does not block receptor-mediated endocytosis at concentrations of up to 300 μM (unpublished reports).
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常规说明
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute -
化学结构
性能
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化学名称
2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-6-sulfonic acid potassium salt -
分子量
420.48 -
分子式
C19H13KN2O5S -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100mM and in water to 25mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
相关产品
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实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120686 被引用在 1 文献中.
- Liu Y et al. Extracellular ATP drives breast cancer cell migration and metastasis via S100A4 production by cancer cells and fibroblasts. Cancer Lett 430:1-10 (2018). PubMed: 29733962