概述

  • 产品名称Anti-Pirh2抗体
    参阅全部 Pirh2 一抗
  • 描述
    兔多克隆抗体to Pirh2
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N terminal region of human Pirh2.

  • 阳性对照
    • HL60 cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab80103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/50 - 1/100. Predicted molecular weight: 30 kDa.

靶标

  • 功能Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 CHY-type zinc finger.
    Contains 1 CTCHY-type zinc finger.
    Contains 1 RING-type zinc finger.
  • 翻译后修饰Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability.
  • 细胞定位Nucleus. Nucleus speckle. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Androgen receptor N terminal interacting protein antibody
    • Androgen receptor N-terminal-interacting protein antibody
    • ARNIP antibody
    • CH-rich-interacting match with PLAG1 antibody
    • CHIMP antibody
    • E3 ubiquitin-protein ligase Pirh2 antibody
    • hARNIP antibody
    • hPirh2 antibody
    • p53 induced protein with a RING H2 domain antibody
    • p53-induced RING-H2 protein antibody
    • PIRH2E antibody
    • PIRH2F antibody
    • PRO1996 antibody
    • RCHY1 antibody
    • Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase antibody
    • RING finger and CHY zinc finger domain-containing protein 1 antibody
    • RING finger protein 199 antibody
    • RNF199 antibody
    • ZCHY antibody
    • ZFP 363 antibody
    • zinc finger CHY type antibody
    • Zinc finger protein 363 antibody
    • ZN363_HUMAN antibody
    • ZNF363 antibody
    see all

Anti-Pirh2 antibody 图像

  • Anti-Pirh2 antibody (ab80103) at 1/50 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 30 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 36 kDa. We are unsure as to the identity of these extra bands.

Anti-Pirh2 antibody (ab80103)参考文献

ab80103 has not yet been referenced specifically in any publications.

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